When Ms. Frizzle's class plans a trip to the planetarium, it's closed for repairs! Never one to be stopped, the amazing teacher takes her students on a field trip through the actual solar system instead. Boarding the magical school bus, they blast off into space, visiting the moon, each planet, and even the asteroid belt. Their adventure turns risky when Ms. Frizzle gets separated from the bus, leaving the class to navigate the wonders and dangers of space on their own to find their way home.